I dont think there should be too much to worry about.
When facing destroyers theres an easy recipe that works like a charm.
A solid minion army with death nova, along with skills that deal cold damage from death magic. An icy veins healing necro also works well. Putrid bile is also a good option to put in. When there also is to mesmers applying various hexes, Destroyers dont have enough hex removal to counter that.
Use alkars acid yourself, works miracles, as it deals 120 AoE dmg, and applys cracked armor.
Enjoy
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